Astragalus Extract: A Natural Defense Against Sun-Induced Skin Aging

Written by Age Reverse

AgeReverse is dedicated to science-backed solutions for longevity, cellular health, and anti-aging. By targeting the 12 Hallmarks of Aging, we develop innovative supplements and skincare to help you live younger, healthier, and longer.

March 1, 2025

Why Sunlight Ages Your Skin

Prolonged exposure to ultraviolet B (UVB) rays damages skin at the cellular level. It triggers oxidative stress, breaks down collagen, depletes moisture, and accelerates wrinkle formation.

Fortunately, nature offers powerful compounds to counteract this damage—and Astragalus extract is one of the most promising.

Study Objective: Can Astragalus Protect the Skin?

A groundbreaking study explored how Astragalus extract might defend skin cells from UVB-induced aging and oxidative stress. Researchers focused on:

⚬ Human Dermal Fibroblasts (HDF) responsible for collagen production
⚬ HaCaT Keratinocytes  support the skin’s outer layer and hydration

Key Findings of the Study

(1) Reduced Oxidative Stress & Collagen Breakdown

Astragalus significantly lowered MMP-1, MMP-9, and MMP-13—enzymes that degrade collagen
It reduced reactive oxygen species (ROS), the free radicals responsible for cellular damage

(2) Boosted Collagen Production

Increased levels of Collagen I, which supports skin structure and elasticity

(3) Improved Cellular Resilience

⚬ Enhanced viability of cells exposed to oxidative stress
⚬ Maintained collagen levels under hydrogen peroxide (H₂O₂) stress

(4) Enhanced Skin Hydration

⚬ Increased hyaluronic acid synthesis
⚬ Elevated key hydration markers: filaggrin and serine palmitoyltransferase (SPT)

Why This Matters for Aging & Skin Health

Skin aging isn’t just cosmetic—it’s a reflection of deeper cellular stress. This study shows Astragalus can:

⚬ Protect structural proteins like collagen
⚬ Reduce oxidative stress that accelerates aging
⚬ Improve moisture retention, crucial for smooth, youthful skin

Together, these benefits contribute to a healthier, more resilient complexion.

How AgeReverse Uses Astragalus

Astragalus Extract, the active molecule in Astragalus, is a foundational part of our AgeReverse Complex, featured in:

⚬ Senolytic Solution – removes damaged cells, promotes skin regeneration
⚬ Resurge Supplement – supports telomere function, cellular energy, and antioxidant defenses
⚬ Multi Defense Face Cream SPF 50+ – protects skin from environmental damage, including UV exposure

Protect Your Skin from the Inside Out

Sunlight is essential—but unprotected exposure accelerates aging. Astragalus offers a plant-powered way to reinforce your skin’s defenses.

Restore Youthful Vitality with Resurge

Take control of aging with Resurge, your ultimate anti-aging & longevity supplement. Experience the benefits of science-backed ingredients that nourish your body from the inside out.

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