Fisetin & Quercetin: Senolytic Agents for Cellular Senescence & Longevity

Written by Age Reverse

AgeReverse is dedicated to science-backed solutions for longevity, cellular health, and anti-aging. By targeting the 12 Hallmarks of Aging, we develop innovative supplements and skincare to help you live younger, healthier, and longer.

October 15, 2024

What Are Senolytics & Why Are They Important?

Aging leads to an accumulation of senescent cells, which:

⚬ Stop dividing but remain active, releasing harmful inflammatory signals
⚬ Contribute to chronic inflammation & tissue dysfunction
⚬ Accelerate age-related diseases like cardiovascular disease & neurodegeneration

Senolytic compounds like Fisetin & Quercetin selectively clear these aging cells, promoting cellular renewal.

Fisetin: A Natural Senolytic & Longevity Booster

Fisetin is a flavonoid found in strawberries, apples, persimmons, onions, and cucumbers. It has been studied for its:

⚬ Senolytic Activity – Clears senescent cells while preserving healthy ones
⚬ Antioxidant & Anti-Inflammatory Effects – Reduces oxidative stress and chronic inflammation
⚬ Neuroprotection – Supports brain health and reduces risk of neurodegenerative diseases
⚬ Telomere Extension – Helps protect chromosome integrity and slow cellular aging

Fisetin activates sirtuins—key longevity proteins involved in DNA repair and metabolic regulation.

Quercetin: Supporting Cellular Health & Inflammation Reduction

Quercetin is another flavonoid found in apples, berries, onions, and leafy greens. It plays a key role in:

⚬ Senolytic Function – Eliminates senescent cells & prevents their harmful effects
⚬ Anti-Inflammatory Action – Blocks harmful pro-inflammatory molecules (SASP)
⚬ Antioxidant Defense – Neutralizes free radicals & protects against oxidative damage
⚬ Immune Support – Enhances immune system function & tissue repair

Quercetin selectively triggers pathways that cause senescent cells to self-destruct, reducing chronic inflammation.

How Fisetin & Quercetin Work Together to Combat Aging

Because aging is driven by senescent cell accumulation, a combination of senolytic agents like Fisetin & Quercetin offers a powerful approach:

⚬ Synergistic Senolytic Action – Works together to remove harmful aged cells
⚬ Reduces Chronic Inflammation – Blocks inflammatory pathways linked to aging
⚬ Enhances Cellular Repair & Regeneration – Promotes longevity & tissue renewal

These compounds are among the most well-researched natural senolytics available.

How AgeReverse Resurge Utilizes Fisetin & Quercetin

AgeReverse Resurge includes Fisetin & Quercetin to:

⚬ Support senescent cell clearance & cellular detoxification
⚬ Reduce inflammation & oxidative stress for healthier aging
⚬ Promote brain, heart, and immune system longevity

These two ingredients make Resurge one of the most advanced anti-aging formulations available today.

Powerful Senolytics: Clearing the Path to Longevity

Fisetin and Quercetin are two groundbreaking natural compounds known as senolytics, capable of selectively removing senescent (aged) cells. Recent studies demonstrate that fisetin is highly effective in targeting and clearing senescent cells, thereby reducing inflammation and promoting healthier aging [source]. Similarly, quercetin has been extensively studied for its role in preventing cellular aging and managing age-related diseases by mitigating inflammation and oxidative stress [source].

At AgeReverse™, incorporating these powerful senolytics into our supplements ensures we actively support your body’s ability to rejuvenate from within, clearing away cellular debris to reveal younger, healthier cells beneath.

Take Charge of Your Cellular Health

Senescent cells drive chronic inflammation and tissue aging. With Fisetin & Quercetin, you can clear out these aging cells and slow the aging process. Discover the benefits with AgeReverse Resurge today!

Restore Youthful Vitality with Resurge

Take control of aging with Resurge, your ultimate anti-aging & longevity supplement. Experience the benefits of science-backed ingredients that nourish your body from the inside out.

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